Resources in the field of Psychedelics and Spirituality


  • Ganz, P. A. The 'three Ps' of cancer survivorship care. BMC Med 9, 14, doi:10.1186/1741-7015-9-14 (2011).
  • Passie, T., Seifert, J., Schneider, U. & Emrich, H. M. The pharmacology of psilocybin. Addict Biol 7, 357-364, doi:10.1080/1355621021000005937 (2002).
  • Phelps, J. Developing Guidelines and Competencies for the Training of Psychedelic Therapists. Journal of Humanistic Psychology 57, 450-487, doi:10.1177/0022167817711304 (2017).
  • Griffiths, R. R. et al. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. J Psychopharmacol 30, 1181-1197, doi:10.1177/0269881116675513 (2016).
  • Ross, S. et al. Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial. J Psychopharmacol 30, 1165-1180, doi:10.1177/0269881116675512 (2016).
  • Rosenbaum, D. et al. Psychedelics for psychological and existential distress in palliative and cancer care. Current oncology (Toronto, Ont.) 26, 225-226, doi:10.3747/co.26.5009 (2019).
  • Pollan, M. How to change your mind: the new science of psychedelics.
  • Engel, G. L. A life setting conducive to illness. The giving-up--given-up complex. Bull Menninger Clin 32, 355-365 (1968).
  • Grassi, L. & Nanni, M. G. Demoralization syndrome: New insights in psychosocial cancer care. Cancer 122, 2130-2133, doi:10.1002/cncr.30022 (2016).
  • Robinson, S., Kissane, D. W., Brooker, J. & Burney, S. A systematic review of the demoralization syndrome in individuals with progressive disease and cancer: a decade of research. Journal of pain and symptom management 49, 595-610, doi:10.1016/j.jpainsymman.2014.07.008 (2015).
  • van der Spek, N. et al. Cost-utility analysis of meaning-centered group psychotherapy for cancer survivors. Psycho-oncology 27, 1772-1779, doi:10.1002/pon.4726 (2018).
  • van der Spek, N. et al. Efficacy of meaning-centered group psychotherapy for cancer survivors: a randomized controlled trial. Psychological medicine 47, 1990-2001, doi:10.1017/s0033291717000447 (2017).
  • Spiegel, D. & Yalom, I. D. A support group for dying patients. Int J Group Psychother 28, 233-245, doi:10.1080/00207284.1978.11491609 (1978).
  • Spiegel, D. Psilocybin-assisted psychotherapy for dying cancer patients - aiding the final trip. J Psychopharmacol 30, 1215-1217, doi:10.1177/0269881116675783 (2016).
  • Spiegel, D. & Cordova, M. Supportive-expressive group therapy and life extension of breast cancer patients: Spiegel et al. (1989). Adv Mind Body Med 17, 38-41 (2001).
  • Zaider, T. I., Kissane, D. W., Schofield, E., Li, Y. & Masterson, M. Cancer-related communication during sessions of family therapy at the end of life. Psychooncology 29, 373-380, doi:10.1002/pon.5268 (2020).
  • Anderson, B. T. et al. Psilocybin-assisted group therapy for demoralized older long-term AIDS survivor men: An open-label safety and feasibility pilot study. EClinicalMedicine, 100538, doi:https://doi.org/10.1016/j.eclinm.2020.100538 (2020).
  • Whelan, A. & Johnson, M. I. Lysergic acid diethylamide and psilocybin for the management of patients with persistent pain: a potential role? Pain Manag 8, 217-229, doi:10.2217/pmt-2017-0068 (2018).
  • Kast, E. C. & Collins, V. J. STUDY OF LYSERGIC ACID DIETHYLAMIDE AS AN ANALGESIC AGENT. Anesth Analg 43, 285-291 (1964).
  • Grof, S., Goodman, L. E., Richards, W. A. & Kurland, A. A. LSD-assisted psychotherapy in patients with terminal cancer. Int Pharmacopsychiatry 8, 129-144, doi:10.1159/000467984 (1973).
  • Chwistek, M. & Ewerth, N. Opioids and Chronic Pain in Cancer Survivors: Evolving Practice for Palliative Care Clinics. J Palliat Med 19, 254, doi:10.1089/jpm.2015.0471 (2016).
  • Medicine, I. o. & Council, N. R. From Cancer Patient to Cancer Survivor: Lost in Transition.  (The National Academies Press, 2006).
  • Paice, J. A. et al. Management of Chronic Pain in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 34, 3325-3345, doi:10.1200/jco.2016.68.5206 (2016).
  • Temel, J. S., Shaw, A. T. & Greer, J. A. Challenge of Prognostic Uncertainty in the Modern Era of Cancer Therapeutics. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 34, 3605-3608, doi:10.1200/JCO.2016.67.8573 (2016).
  • Sledge, G. W. Patients and Physicians in the Era of Modern Cancer Care. Jama 321, 829-830, doi:10.1001/jama.2018.17334 (2019).
  • Stern, A. P. Surviving Cancer in the Midst of a Treatment Revolution: Hope and Delusion. JAMA oncology 4, 1667, doi:10.1001/jamaoncol.2018.4430 (2018).
  • Langbaum, T. & Smith, T. J. Time to Study Metastatic-Cancer Survivorship. The New England journal of medicine 380, 1300-1302, doi:10.1056/NEJMp1901103 (2019).
  • Swift, T. C. et al. Cancer at the Dinner Table: Experiences of Psilocybin-Assisted Psychotherapy for the Treatment of Cancer-Related Distress. Journal of Humanistic Psychology 57, 488-519, doi:10.1177/0022167817715966 (2017).
  • Marzorati, C., Riva, S. & Pravettoni, G. Who Is a Cancer Survivor? A Systematic Review of Published Definitions. J Cancer Educ 32, 228-237, doi:10.1007/s13187-016-0997-2 (2017).
  • Geerse, O. P., Lakin, J. R., Berendsen, A. J., Alfano, C. M. & Nekhlyudov, L. Cancer survivorship and palliative care: Shared progress, challenges, and opportunities. Cancer 124, 4435-4441, doi:10.1002/cncr.31723 (2018).
  • Halpern, M. T. et al. Models of Cancer Survivorship Care: Overview and Summary of Current Evidence. Journal of oncology practice 11, e19-27, doi:10.1200/jop.2014.001403 (2015).
  • Shakeel, S., Tung, J., Rahal, R. & Finley, C. Evaluation of Factors Associated With Unmet Needs in Adult Cancer Survivors in Canada. JAMA Netw Open 3, e200506, doi:10.1001/jamanetworkopen.2020.0506 (2020).
  • Yazdani, S. & Abdi, S. Brief review: pain management for cancer survivors: challenges and opportunities. Can J Anaesth 61, 745-753, doi:10.1007/s12630-014-0170-5 (2014).
  • Mollica, M. & Nemeth, L. Transition from patient to survivor in African American breast cancer survivors. Cancer Nurs 38, 16-22, doi:10.1097/ncc.0000000000000120 (2015).
  • Schenker, Y., Merlin, J. S. & Quill, T. E. Use of Palliative Care Earlier in the Disease Course in the Context of the Opioid Epidemic: Educational, Research, and Policy Issues. Jama 320, 871-872, doi:10.1001/jama.2018.9739 (2018).
  • Vehling, S. & Philipp, R. Existential distress and meaning-focused interventions in cancer survivorship. Curr Opin Support Palliat Care 12, 46-51, doi:10.1097/spc.0000000000000324 (2018).
  • Strang, P., Strang, S., Hultborn, R. & Arnér, S. Existential pain--an entity, a provocation, or a challenge? Journal of pain and symptom management 27, 241-250, doi:10.1016/j.jpainsymman.2003.07.003 (2004).
  • LeMay, K. & Wilson, K. G. Treatment of existential distress in life threatening illness: a review of manualized interventions. Clin Psychol Rev 28, 472-493, doi:10.1016/j.cpr.2007.07.013 (2008).
  • Kissane, D. W. Demoralization: a life-preserving diagnosis to make for the severely medically ill. J Palliat Care 30, 255-258 (2014).
  • Townsend, K. Demoralisation in palliative care. The Lancet. Oncology 19, 168, doi:10.1016/s1470-2045(18)30020-2 (2018).
  • Jong, C., Kissane, D., Geessink, R. & Velden, D. Demoralization in Opioid Dependent Patients: A Comparative Study with Cancer Patients and Community Subjects. The Open Addiction Journal 1, doi:10.2174/1874941000801010007 (2008).
  • de Figueiredo, J. M. & Griffith, J. L. Chronic Pain, Chronic Demoralization, and the Role of Psychotherapy. Journal of Contemporary Psychotherapy 46, 167-177, doi:10.1007/s10879-016-9331-x (2016).
  • Frankl, V. E., Lasch, I., Kushner, H. S. & Winslade, W. J. Man's search for meaning.  (2006).
  • Yalom, I. D. Existential psychotherapy.  (1980).
  • Frank, J. The role of hope in psychotherapy. Int J Psychiatry 5, 383-395 (1968).
  • Ferrer, R. A. & Padgett, L. S. Leveraging Affective Science to Maximize the Effectiveness of Palliative Care. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 33, 4229-4230, doi:10.1200/jco.2015.62.8883 (2015).
  • Clarke, D. M. & Kissane, D. W. Demoralization: its phenomenology and importance. Aust N Z J Psychiatry 36, 733-742, doi:10.1046/j.1440-1614.2002.01086.x (2002).
  • Robinson, S. et al. Refinement and revalidation of the demoralization scale: The DS-II-external validity. Cancer 122, 2260-2267, doi:10.1002/cncr.30012 (2016).
  • Robinson, S. et al. Refinement and revalidation of the demoralization scale: The DS-II-internal validity. Cancer 122, 2251-2259, doi:10.1002/cncr.30015 (2016).
  • Belar, A. et al. Multicenter Study of the Psychometric Properties of the New Demoralization Scale (DS-II) in Spanish-Speaking Advanced Cancer Patients. Journal of pain and symptom management 57, 627-634, doi:10.1016/j.jpainsymman.2018.11.016 (2019).
  • Kissane, D. W. The contribution of demoralization to end of life decisionmaking. Hastings Cent Rep 34, 21-31 (2004) Ong, C. K. & Forbes, D. Embracing Cicely Saunders's concept of total pain. Bmj 331, 576, doi:10.1136/bmj.331.7516.576-d (2005).
  • de Figueiredo, J. M. Demoralization and Psychotherapy: A Tribute to Jerome D. Frank, MD, PhD (1909-2005). Psychother Psychosom 76, 129-133, doi:10.1159/000099839 (2007).
  • Robinson, S., Kissane, D. W., Brooker, J., Hempton, C. & Burney, S. The Relationship Between Poor Quality of Life and Desire to Hasten Death: A Multiple Mediation Model Examining the Contributions of Depression, Demoralization, Loss of Control, and Low Self-worth. Journal of pain and symptom management 53, 243-249, doi:10.1016/j.jpainsymman.2016.08.013 (2017).
  • Byock, I. Taking Psychedelics Seriously. J Palliat Med 21, 417-421, doi:10.1089/jpm.2017.0684 (2018)
  • Meier, D. E. et al. A National Strategy For Palliative Care. Health Aff (Millwood) 36, 1265-1273, doi:10.1377/hlthaff.2017.0164 (2017).
  • Kelley, A. S. & Morrison, R. S. Palliative Care for the Seriously Ill. The New England journal of medicine 373, 747-755 (2015).
  • Kavalieratos, D. et al. Association Between Palliative Care and Patient and Caregiver Outcomes: A Systematic Review and Meta-analysis. Jama 316, 2104-2114, doi:10.1001/jama.2016.16840 (2016).
  • Rabow, M. et al. Moving upstream: a review of the evidence of the impact of outpatient palliative care. J Palliat Med 16, 1540-1549, doi:10.1089/jpm.2013.0153 (2013).
  • Temel, J. S. et al. Early palliative care for patients with metastatic non-small-cell lung cancer. The New England journal of medicine 363, 733-742, doi:10.1056/NEJMoa1000678 (2010).
  • Sinclair, C. T. Master Clinician Series: Survivorship and Upstream Palliative Care, <https://www.capc.org/events/case-reviews/how-palliative-care-can-help-patients-survivorship/> (2020).
  • Ferrell, B. R., Twaddle, M. L., Melnick, A. & Meier, D. E. National Consensus Project Clinical Practice Guidelines for Quality Palliative Care Guidelines, 4th Edition. J Palliat Med 21, 1684-1689, doi:10.1089/jpm.2018.0431 (2018).
  • Ahluwalia, S. C. et al. A Systematic Review in Support of the National Consensus Project Clinical Practice Guidelines for Quality Palliative Care, Fourth Edition. Journal of pain and symptom management 56, 831-870, doi:10.1016/j.jpainsymman.2018.09.008 (2018).
  • Chwistek, M. Recent advances in understanding and managing cancer pain. F1000Res 6, 945, doi:10.12688/f1000research.10817.1 (2017).
  • van den Beuken-van Everdingen, M. H., Hochstenbach, L. M., Joosten, E. A., Tjan-Heijnen, V. C. & Janssen, D. J. Update on Prevalence of Pain in Patients With Cancer: Systematic Review and Meta-Analysis. Journal of pain and symptom management 51, 1070-1090.e1079, doi:10.1016/j.jpainsymman.2015.12.340 (2016).
  • Bhatnagar, S. & Gupta, M. Evidence-based Clinical Practice Guidelines for Interventional Pain Management in Cancer Pain. Indian J Palliat Care 21, 137-147, doi:10.4103/0973-1075.156466 (2015).
  • Meuser, T. et al. Symptoms during cancer pain treatment following WHO-guidelines: a longitudinal follow-up study of symptom prevalence, severity and etiology. Pain 93, 247-257, doi:10.1016/s0304-3959(01)00324-4 (2001).
  • Bruera, E. & Del Fabbro, E. Pain Management in the Era of the Opioid Crisis. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 38, 807-812, doi:10.1200/edbk_208563 (2018).
  • Arthur, J. & Bruera, E. Balancing opioid analgesia with the risk of nonmedical opioid use in patients with cancer. Nature reviews. Clinical oncology 16, 213-226, doi:10.1038/s41571-018-0143-7 (2019).
  • Loren, A. W. Harder to Treat Than Leukemia - Opioid Use Disorder in Survivors of Cancer. The New England journal of medicine 379, 2485-2487, doi:10.1056/NEJMp1812850 (2018).
  • Arthur, J. A. et al. Aberrant Opioid Use and Urine Drug Testing in Outpatient Palliative Care. J Palliat Med 19, 778-782, doi:10.1089/jpm.2015.0335 (2016).
  • Arthur, J. et al. Outcomes of a Specialized Interdisciplinary Approach for Patients with Cancer with Aberrant Opioid-Related Behavior. The oncologist 23, 263-270, doi:10.1634/theoncologist.2017-0248 (2018).
  • Merlin, J. S. et al. Managing Opioids, Including Misuse and Addiction, in Patients With Serious Illness in Ambulatory Palliative Care: A Qualitative Study. The American journal of hospice & palliative care 37, 507-513, doi:10.1177/1049909119890556 (2020).
  • Merlin, J. S., Childers, J. & Arnold, R. M. Chronic pain in the outpatient palliative care clinic. The American journal of hospice & palliative care 30, 197-203, doi:10.1177/1049909112443587 (2013).
  • Goodlev, E. R. et al. Managing Cancer Pain, Monitoring for Cancer Recurrence, and Mitigating Risk of Opioid Use Disorders: A Team-Based, Interdisciplinary Approach to Cancer Survivorship. J Palliat Med 22, 1308-1317, doi:10.1089/jpm.2019.0171 (2019).
  • Flanagan, T. W. & Nichols, C. D. Psychedelics as anti-inflammatory agents. Int Rev Psychiatry 30, 363-375, doi:10.1080/09540261.2018.1481827 (2018).
  • Castellanos, J. P. et al. Chronic pain and psychedelics: a review and proposed mechanism of action. Reg Anesth Pain Med 45, 486-494, doi:10.1136/rapm-2020-101273 (2020).
  • Karst, M., Halpern, J. H., Bernateck, M. & Passie, T. The non-hallucinogen 2-bromo-lysergic acid diethylamide as preventative treatment for cluster headache: an open, non-randomized case series. Cephalalgia 30, 1140-1144, doi:10.1177/0333102410363490 (2010).
  • Sewell, R. A., Halpern, J. H. & Pope, H. G., Jr. Response of cluster headache to psilocybin and LSD. Neurology 66, 1920-1922, doi:10.1212/01.wnl.0000219761.05466.43 (2006).
  • Ramachandran, V., Chunharas, C., Marcus, Z., Furnish, T. & Lin, A. Relief from intractable phantom pain by combining psilocybin and mirror visual-feedback (MVF). Neurocase 24, 105-110, doi:10.1080/13554794.2018.1468469 (2018).
  • Dyck, E. Psychedelics and Dying Care: A Historical Look at the Relationship between Psychedelics and Palliative Care. J Psychoactive Drugs 51, 102-107, doi:10.1080/02791072.2019.1581308 (2019).
  • Kelmendi, B., Corlett, P., Ranganathan, M., D'Souza, C. & Krystal, J. H. The role of psychedelics in palliative care reconsidered: A case for psilocybin. J Psychopharmacol 30, 1212-1214, doi:10.1177/0269881116675781 (2016).
  • Back, A. L. What Psilocybin Taught Me, One Year Later. J Palliat Med 23, 1130-1131, doi:10.1089/jpm.2020.0018 (2020).
  • Cancer and hallucinogens: a long, strange trip. The Lancet. Oncology 11, 603, doi:10.1016/s1470-2045(10)70153-4 (2010).
  • VanderWeele, T. J. On the promotion of human flourishing. Proc Natl Acad Sci U S A 114, 8148-8156, doi:10.1073/pnas.1702996114 (2017).
  • Haufe, M., Leget, C., Potma, M. & Teunissen, S. How can existential or spiritual strengths be fostered in palliative care? An interpretative synthesis of recent literature. BMJ Support Palliat Care, doi:10.1136/bmjspcare-2020-002379 (2020).
  • Nolan, S. Hope beyond (redundant) hope: how chaplains work with dying patients. Palliat Med 25, 21-25, doi:10.1177/0269216310380297 (2011).
  • Jacobs, M. R. What are we doing here? Chaplains in contemporary health care. Hastings Cent Rep 38, 15-18, doi:10.1353/hcr.0.0079 (2008)
  • Idler, E. L., Grant, G. H., Quest, T., Binney, Z. & Perkins, M. M. Practical Matters and Ultimate Concerns, “Doing,” and “Being”: A Diary Study of the Chaplain's Role in the Care of the Seriously Ill in an Urban Acute Care Hospital. Journal for the Scientific Study of Religion 54, 722-738, doi:10.1111/jssr.12235 (2015)
  • Center for Contemplative Science and Compassion-Based Ethics, <https://compassion.emory.edu/index.html>
  • Cockram, C. A., Doros, G. & de Figueiredo, J. M. Diagnosis and measurement of subjective incompetence: the clinical hallmark of demoralization. Psychother Psychosom 78, 342-345, doi:10.1159/000235737 (2009).
  • Gardner, C. & Kleinman, A. Medicine and the Mind - The Consequences of Psychiatry's Identity Crisis. The New England journal of medicine 381, 1697-1699, doi:10.1056/NEJMp1910603 (2019).
  • Johnson, M., Richards, W. & Griffiths, R. Human hallucinogen research: guidelines for safety. J Psychopharmacol 22, 603-620, doi:10.1177/0269881108093587 (2008).
  • Yaden, D. B. et al. The development of the Awe Experience Scale (AWE-S): A multifactorial measure for a complex emotion. The Journal of Positive Psychology 14, 474-488, doi:10.1080/17439760.2018.1484940 (2019).
  • Barrett, F. S., Bradstreet, M. P., Leoutsakos, J. S., Johnson, M. W. & Griffiths, R. R. The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms. J Psychopharmacol 30, 1279-1295, doi:10.1177/0269881116678781 (2016).
  • Roseman, L. et al. Emotional breakthrough and psychedelics: Validation of the Emotional Breakthrough Inventory. J Psychopharmacol 33, 1076-1087, doi:10.1177/0269881119855974 (2019)
  • Zigmond, A. S. & Snaith, R. P. The hospital anxiety and depression scale. Acta Psychiatr Scand 67, 361-370, doi:10.1111/j.1600-0447.1983.tb09716.x (1983).
  • Barrett, F. S. & Griffiths, R. R. Classic Hallucinogens and Mystical Experiences: Phenomenology and Neural Correlates. Curr Top Behav Neurosci 36, 393-430, doi:10.1007/7854_2017_474 (2018).
  • Barrett, F. S., Johnson, M. W. & Griffiths, R. R. Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin. J Psychopharmacol 29, 1182-1190, doi:10.1177/0269881115609019 (2015).
  • Kaur, N. et al. Evaluation of a modified version of the Posttraumatic Growth Inventory-Short Form. BMC Med Res Methodol 17, 69, doi:10.1186/s12874-017-0344-2 (2017)
  • Lee, R. & Robbins, S. Measuring Belongingness: The Social Connectedness and the Social Assurance Scales. Journal of Counseling Psychology 42, 232-241, doi:10.1037/0022-0167.42.2.232 (1995).
  • Mundt, J. C., Marks, I. M., Shear, M. K. & Greist, J. H. The Work and Social Adjustment Scale: a simple measure of impairment in functioning. Br J Psychiatry 180, 461-464, doi:10.1192/bjp.180.5.461 (2002).